I’ll take one Cheap and Delicious cancer burger, please🍔
But $hit it was 99 cents
A ‘comedian’ called Sophie Hagen absolutely went off on one on twitter about this Cancer Research ad.
Apparently stating scientifically proven facts (being obese increases your cancer risk and most obese people could be not obese if they really tried) is now ‘fat shaming’ and there should be public petitions against it.
@Nellybert , while I believe that obesity is a significant problem (dare I say a growing problem?), I do have an issue with saying it causes cancer. Correlation does not equal causation. https://goo.gl/images/7smp7B
The above site shows a graph correlating obesity very nicely with credit card debt as a percentage of the GDP.
The cancer risk may just as likely be caused by food choices (obese people in some Mediterranean areas may not have as high a cancer risk due to dietary differences). Additionally, I'm thinking the sun exposure directly causes more cancers than those correlated with obesity
@occasionalmutant, Boiled right down to the level I could understand it: being obese leads to higher levels of certain hormones being present in the body. Higher levels of those hormones cause higher levels of cell replication/multiplication/division - not sure the best word. Increasing that increases the chance of cell mutation (there’s a certain chance of mutation each time, so it happening more pushes up the overall chances of mutation). Each mutation has a chance of being cancer.
So basically - being obese increases the likelihood of an event which can cause cancer.
@occasionalmutant, obesity is the second leading cause of cancer (smoking is #1) of preventable cancers which are 42% of all cancers.
@Branded, no it is not. Cite a source if you have one. Skin cancer (one million cases a year) is usually caused by sun exposure, and is more prevalent than the next ten cancers combined (lung, breast, prostate, colorectal, bladder, kidney, liver, lymphomas). And literature says that there is a Correlation, not a proven cause, associated with obesity, diet, and inactivity. It doesn't say obesity alone, it combines obesity with diet and inactivity. While related, they are not the same. And correlation does not prove causation. The previous commenter said he thought it was hormone related, but I think he meant inflammatory mediator related. Either way, cause and effect has not been established, and skin cancers far surpass lung cancers.
@Nellybert , as a research intern in Norway studying this EXACT phenomena, you are exactly correct
@occasionalmutant, TY - JOUR AU - Calle, Eugenia E. AU - Kaaks, Rudolf TI - Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms JO - Nature Reviews Cancer PY - 2004/08/01/online VL - 4 SP - 579 EP - PB - Nature Publishing Group SN - UR - http://dx.doi.org/10.1038/nrc1408 L3 - 10.1038/nrc1408 M3 - Review Article L3 - ER -
Zhang X, Shu XO, Yang G, Li H, Cai H, Gao YT, Zheng W. Abdominal adiposity and mortality in Chinese women. Arch Intern Med. 2007; 167: 886–892.
@ajr12100, two sources from world renowned sources with hard proof that obesity causes cancer. Not only that but these are from over a decade ago- and the evidence is only stronger now. If you actually think obesity doesn’t cause cancer you’re either in denial or a conspiracy theorist.
Cause and effect has been established- for example- estrogen produced in adipose tissue causes breast cancer. Another direct cause and effect relationship can be found through type 2 diabetes (which obesity can cause)- cells stop responding to insulin and higher glucose levels cause increased insulin production. The insulin acts as a mitogen to cancer cells.
@ajr12100, and that’s not even getting into the potential of cytokines produced in excess in adipose tissue having the potential to cause cancer
These are all a direct result of obesity itself- that is being fat, having extra adipose tissue. Not related to exercise or diet, although obviously these can help or hurt your chances of getting cancer as well
@occasionalmutant, On skin cancer - the advert is by Cancer Research UK and relates to the UK, where the ad was placed. Skin cancer is 5th on the list here (15k/annum, with breast, prostate, lung and bowel getting about 50k/annum here).
Obesity can lead to higher insulin levels, which raises growth hormone levels and increases cell division - higher risk of cancerous mutation. More fat cells means more cytokines, which means more cell division - higher risk of cancerous mutation. After menopause, oestrogen released by fat cells cause more cell division in the breast & womb - higher risk of cancerous mutation.
@occasionalmutant, Also, what’s your source on skin cancer? The data I found (from the World Cancer Research Fund) put skin cancer as the 19th most common (1.9% of all new cancer diagnoses, 232,000 per annum). The top 5 were lung, breast, colon, prostate and stomach - they make up about 50% of new cancer diagnoses (almost 7 million per annum).
@Nellybert , I'll use your source. The World Cancer Research Fund International lists the most common cancers, EXCLUDING NON MELANOMA skin cancers (NMSCs). If you include NMSCs, which are 20 times as prevalent as melanoma skin cancers, then over 4 million skin cancers pet year occur. I guess I could say that in the last winter Olympics, Germany won the most medals (excluding Norway), but that seems to omit the actual facts. Also, increased cell reproduction can be inferred to increase cancer risk, because chance mutations are more likely, but that does not mandate increases in cancer, as most mutations will not be cancerous. If we use the logic that cell reproduction rates correlate to cancer rates, then the organs with the highest reproductive rates should have the highest cancer incidence. That would be the intestinal epithelium (2-4 days), white blood cells (1 -5 days). So clearly, other factors (environment, genetics) play a more significant role.
@occasionalmutant, You are correct, I did not notice that exclusion at the start of the page. Although I understand the the exclusion is because non-melanoma skin cancers are so easily treatable and rarely fatal that they’re not always reported. They kill about 2,000 people a year - so if 4million are diagnosed each year, that’s a 0.05% mortality rate. Not so scary as the 10,000 dying from the rarer melanomas.
And yes, genetics could well be a factor in many cases - but the key word in the advert is PREVENTABLE. I can lose weight, can’t do a lot about my DNA.
And no, most mutations will not be cancerous - but if 1 in a million is, increasing the number of mutations will likely increase the risk of cancer.
Why is this funny? Edit: the gif didn't load..